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Anti-CD14 Polyclonal Antibody
產(chǎn)品簡介：

Anti-CD14 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human

產(chǎn)品型號：K101533P

更新時間：2022-08-15

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產(chǎn)品介紹

Anti-CD14 Polyclonal Antibody

英文名稱Anti-CD14 Polyclonal Antibody
宿主Rabbit
別名CD14;Monocyte differentiation antigen CD14;CD14 molecule;LPS-R;Mo2
應(yīng)用WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human
蛋白分子量40kDa
Gene ID929
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human CD14
性狀液體
Public Immunogen RangeA synthetic peptide of human CD14
Subcellular LocationsCell membrane GPI-anchor Lipid-anchor Secreted
Swiss ProtP08571
克隆類型Polyclonal Antibody
背景資料Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.

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