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Anti-Delta4 Polyclonal Antibody
產(chǎn)品簡介:

Anti-Delta4 Polyclonal Antibody
應用 WB
稀釋比例WB 1:3000.
交叉反應Human Mouse Rat

產(chǎn)品型號:K106504P

更新時間:2022-08-15

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產(chǎn)品介紹

Anti-Delta4 Polyclonal Antibody

英文名稱Anti-Delta4 Polyclonal Antibody
宿主Rabbit
別名DLL4;AOS6;DLL 4;hdelta2;MGC126344
應用WB
稀釋比例WB 1:3000.
交叉反應Human Mouse Rat
蛋白分子量75kDa
Gene ID54567
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human Delta4
性狀液體
Public Immunogen RangeA synthetic peptide of human Delta4
Subcellular LocationsCell membrane
Swiss ProtQ9NR61
克隆類型Polyclonal Antibody
背景資料The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium.

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