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Anti-SOCS1 Polyclonal Antibody
產(chǎn)品簡介：

Anti-SOCS1 Polyclonal Antibody
應(yīng)用 WB IHC
稀釋比例WB 1:2000-5000.IHC 1:50-200.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號：K106494P

更新時間：2022-08-15

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產(chǎn)品介紹

Anti-SOCS1 Polyclonal Antibody

英文名稱Anti-SOCS1 Polyclonal Antibody
宿主Rabbit
別名CIS1;CISH1;JAB;SOCS-1;SSI-1;SSI1;TIP-3;TIP3
應(yīng)用WB IHC
稀釋比例WB 1:2000-5000.IHC 1:50-200.
交叉反應(yīng)Human Mouse Rat
蛋白分子量33kDa
Gene ID8651
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human SOCS1
性狀液體
Public Immunogen RangeA synthetic peptide of human SOCS1
Subcellular LocationsCytoplasm
Swiss ProtO15524
克隆類型Polyclonal Antibody
背景資料This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

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