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Anti-SIRT1 Polyclonal Antibody
產(chǎn)品簡介:

Anti-SIRT1 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號:K106486P

更新時間:2022-08-15

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產(chǎn)品介紹

Anti-SIRT1 Polyclonal Antibody

英文名稱Anti-SIRT1 Polyclonal Antibody
宿主Rabbit
別名SIR2;SIR2alpha;SIR2L1;SIR2-like protein 1;Hsir2
應(yīng)用WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat
蛋白分子量130kDa
Gene ID23411
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human SIRT1
性狀液體
Public Immunogen RangeA synthetic peptide of human SIRT1
Subcellular LocationsCytoplasm Nucleus Mitochondrion
Swiss ProtQ96EB6
克隆類型Polyclonal Antibody
背景資料This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

 

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