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產(chǎn)品中心抗體Polyclonal AntibodyK106513PAnti-VCAM-1 Polyclonal Antibody
產(chǎn)品型號(hào)：K106513P
更新時(shí)間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
訪 問(wèn) 量 ：906
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產(chǎn)品分類
Anti-VCAM-1 Polyclonal Antibody
| 英文名稱 | Anti-VCAM-1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | INCAM-100;CD106;CUL 5;Cullin5;CUL5_HUMAN |
| 應(yīng)用 | WB IHC |
| 稀釋比例 | WB 1:2000-5000.IHC 1:50-200. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 81kDa |
| Gene ID | 7412 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human VCAM-1 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human VCAM-1 |
| Subcellular Locations | Cytoplasm Nucleus Cell membrane |
| Swiss Prot | P19320 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | VCAM1 is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the integrins alpha4 beta1 (beta 1 integrin VLA4) and alpha4 beta7 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM1 is also expressed by several non endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells. |
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