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Polyclonal Antibody
K106584PAnti-TLR4 Polyclonal Antibody
產(chǎn)品型號(hào):K106584P
更新時(shí)間:2022-08-15
廠商性質(zhì):生產(chǎn)廠家
訪 問 量 :1029
010-50973130
產(chǎn)品分類
英文名稱 | Anti-TLR4 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | ARMD10;CD284;TLR-4;TOLL |
應(yīng)用 | WB |
稀釋比例 | WB 1:500-2000. |
交叉反應(yīng) | Human Mouse Rat |
蛋白分子量 | 73kDa |
Gene ID | 7099 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | Recombinant protein of human TLR4 |
性狀 | 液體 |
Public Immunogen Range | Recombinant protein of human TLR4 |
Subcellular Locations | Cytoplasm Cell membrane |
Swiss Prot | O00206 |
克隆類型 | Polyclonal Antibody |
背景資料 | Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. |
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