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Anti-MDH1 Polyclonal Antibody
產(chǎn)品簡介：

Anti-MDH1 Polyclonal Antibody
應用 WB IHC
稀釋比例WB 1:500-2000. IHC 1:25-100.
交叉反應Human Mouse

產(chǎn)品型號：K106619P

更新時間：2022-08-15

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產(chǎn)品介紹

Anti-MDH1 Polyclonal Antibody

英文名稱Anti-MDH1 Polyclonal Antibody
宿主Rabbit
別名MDH1;HEL-S-32;MDH-s;MDHA;MGC:1375;MOR2
應用WB IHC
稀釋比例WB 1:500-2000. IHC 1:25-100.
交叉反應Human Mouse
蛋白分子量36kDa
Gene ID4190
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human MDH1
性狀液體
Public Immunogen RangeRecombinant protein of human MDH1
Subcellular LocationsCytoplasm
Swiss ProtP40925
克隆類型Polyclonal Antibody
背景資料This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6

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