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Polyclonal Antibody
K106734PAnti-IRAK4 Polyclonal Antibody
產(chǎn)品型號:K106734P
更新時間:2022-08-14
廠商性質(zhì):生產(chǎn)廠家
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產(chǎn)品分類
Anti-IRAK4 Polyclonal Antibody
英文名稱 | Anti-IRAK4 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | IRAK-4;Renal carcinoma antigen NY-REN-64;Interleukin-1 receptor-associated kinase 4 |
應用 | WB IHC |
稀釋比例 | WB 1:500-2000. IHC 1:25-100. |
交叉反應 | Human |
蛋白分子量 | 52kDa |
Gene ID | 51135 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human IRAK4 |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human IRAK4 |
Subcellular Locations | Cytoplasm |
Swiss Prot | Q9NWZ3 |
克隆類型 | Polyclonal Antibody |
背景資料 | Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1. |
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