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Anti-IRAK4 Polyclonal Antibody
產(chǎn)品簡介:

Anti-IRAK4 Polyclonal Antibody
應用 WB IHC
稀釋比例WB 1:500-2000. IHC 1:25-100.
交叉反應Human

產(chǎn)品型號:K106734P

更新時間:2022-08-14

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產(chǎn)品介紹

Anti-IRAK4 Polyclonal Antibody

英文名稱Anti-IRAK4 Polyclonal Antibody
宿主Rabbit
別名IRAK-4;Renal carcinoma antigen NY-REN-64;Interleukin-1 receptor-associated kinase 4
應用WB IHC
稀釋比例WB 1:500-2000. IHC 1:25-100.
交叉反應Human
蛋白分子量52kDa
Gene ID51135
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human IRAK4
性狀液體
Public Immunogen RangeA synthetic peptide of human IRAK4
Subcellular LocationsCytoplasm
Swiss ProtQ9NWZ3
克隆類型Polyclonal Antibody
背景資料Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1.

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