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當(dāng)前位置:首頁產(chǎn)品中心細(xì)胞相關(guān)產(chǎn)品細(xì)胞因子P00026Recombinant Human IL-18細(xì)胞因子

Recombinant Human IL-18細(xì)胞因子
產(chǎn)品簡介:

Recombinant Human Interleukin-18(Recombinant Human IL-18細(xì)胞因子) is produced by our E.coli expression system and the target gene encoding<br>Tyr37-Asp193 is expressed.

產(chǎn)品型號(hào):P00026

更新時(shí)間:2025-08-29

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產(chǎn)品介紹

Recombinant Human IL-18細(xì)胞因子

貨號(hào):P00026

規(guī)格:10ug/50ug/500ug/1mg

Known asInterleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor;Interleukin-1 gamma; IL-1 gamma;GIF; IL-18; IL-1g; IL1F4; MGC12320
Derived fromE.coli
PurityGreater than 95% as determined by reducing SDS-PAGE.Less than 0.1 ng/?g (1 IEU/?g).
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediay at the temperature listed below.
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 10 months
ReconstitutionAlways centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 8X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles.
Amino Acid SequenceYFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMN PPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED
BackgroundInterleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells.

Recombinant Human Interleukin-18 is produced by our E.coli expression system and the target gene encoding
Tyr37-Asp193 is expressed.

 

Recombinant Human IL-18細(xì)胞因子訂購說明:

1、絕大部分產(chǎn)品備有現(xiàn)貨,一般情況下都能訂貨當(dāng)日發(fā)貨。 
2、部分非常用產(chǎn)品,需提前1-2日預(yù)訂,海外期貨則需要提前3-6周預(yù)訂。 
3、部分產(chǎn)品價(jià)格會(huì)因貨期、批次等因素發(fā)生變化,若有變動(dòng)以訂貨當(dāng)日新價(jià)格為準(zhǔn)。 
4、每日訂單截止時(shí)間為16點(diǎn)整,部分城市可到17點(diǎn)整,因超過截止時(shí)間造成當(dāng)日不能發(fā)貨的將于次日安排發(fā)貨。
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